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Case Study: High Correction Factor for Bioburden. How to troubleshoot your bioburden testing?
Case: Company X requested bioburden testing for their product (suture) which will be sterilized by EO. As is routine, the correction factor determination test using repetitive method was conducted first before bioburden testing can be performed. The results showed high correction factor (CF) value, >15.0 corresponding to a low bioburden recovery efficiency percentage. When this CF value was applied to their bioburden results, the bioburden level was higher than expected. This
Aug 273 min read
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Should Membrane Filters Be Pre-Wetted Before Filtration?
In membrane filtration, one common practical question is whether the membrane must be pre-wetted with saline before filtering a sample. This is especially relevant in microbiological testing and bioburden analysis, where filter performance and organism recovery are important considerations. Kumpulan Saintifik (KSFE). (n.d.). Membrane filter, PTFE (hydrophobic) [Photograph]. Retrieved July 30, 2026, from https://www.ksfe.com.my/files/product_image/603/1562649912-l.jpg Is Pre
Jul 303 min read
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